G-6-PD as a Genetic Marker

Abstract

In the past two decades the enormous degree of variability which is characteristic of many human enzymes has unfolded (1,2). Because samples of red blood cells are so easy to obtain they have occupied center stage in the study of enzyme polymorphisms. The investigation of the distribution of various genes for red cell enzymes has been employed to deduce the ebb and flow of human populations. They have been used to establish paternity and as markers in bone marrow transplantation.