Characteristics of the Fc Receptor Induced by Herpes Simplex Virus

Abstract

Studies of the Fc receptor induced [in Y-79 human retinoblastoma cells, Vero African green monkey kidney cells, BALB/C 3T3. SIRC and LY mouse cells] by herpes simplex virus using the 7S EA [erythrocyte, antibody] rosette assay reveal that the percentage of cells showing receptor activity is multiplicity-dependent; the percentage of cells rosetting is independent of the cell cycle phase of the host cell; RNA and viral protein synthesis and probably glycosidation, are required for the induction of the receptor but not viral DNA synthesis; and the receptor is neuraminidase-resistant but trypsin-sensitive.