Anthracycline antitumour agents
- 1 April 1986
- journal article
- review article
- Published by Springer Nature in International Journal of Clinical Pharmacy
- Vol. 8 (2), 109-133
- https://doi.org/10.1007/bf02086146
Abstract
A review of physicochemical and analytical properties of anthracycline antitumour agents is presented. The following subjects are discussed: protolytic equilibria, partition and partition coefficients, self-association, adsorptive properties, metal complexation, spectroscopy and chromatography. Furthermore, the stability of anthracyclines in solutions, in pharmaceutical preparations and in biological media is discussed.Keywords
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