Conformational Studies of Acyclic Organophosphate Esters using Nuclear Magnetic Resonance Spectroscopy

Abstract

The vicinal³¹P—O—C—¹H couplings of a series of acyclic phosphate esters have been measured and rationalized in terms of varying populations of individual rotamers. Variable temperature measurements have been interpreted in terms of the enthalpy and entropy differences between gauche and trans rotational isomers.