THE COMPARATIVE ACTIVITY OF DESOXYCORTICO-STERONE ACETATE AND PROGESTERONE IN ADRENAL-ECTOMIZED RATS
- 1 September 1940
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 27 (3), 473-476
- https://doi.org/10.1210/endo-27-3-473
Abstract
[female] albino rats were adrenalectomized in 2 stages at 25 and 30 days of age. One mg. of desoxycorticosterone acetate daily, intramusc, was beneficial in prolonging life and maintaining considerable growth. Smaller amts., 1/4-1/2 mg. daily, also had a noticeable effect. Adrenalectomized rats injected daily with 1 mg. of progesterone gave a growth curve similar to the growth curve obtained under the same conditions with desoxycorticosterone acetate. The similarity between desoxycorticosterone acetate and progesterone is described.This publication has 4 references indexed in Scilit:
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