A Colon Cancer Cell Line (LIM1215) Derived From a Patient With Inherited Nonpolyposis Colorectal Cancer2
- 1 April 1985
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 74 (4), 759-765
- https://doi.org/10.1093/jnci/74.4.759
Abstract
A new human colon cancer cell line (LIM1215) has been derived from a tumor arising in a member of a family known to have a high incidence of colorectal cancer. The tumor cell line is comprised of small pleomorphic cells that clone in liquid medium and form tumors in immunosuppressed mice. Ultrastructurally, the cells are capable of differentiation, with cells with multiple microvilli and cells resembling goblet cells being present in the one culture. The cells are pseudodiploid and contain a 13p+ marker chromosome.Keywords
This publication has 7 references indexed in Scilit:
- Growth and differentiation of fetal rat small intestinal epithelium in tissue cultureExperimental Cell Research, 1984
- A New Human Breast Carcinoma Cell Line (PMC42) With Stem Cell Characteristics. I. Morphologic CharacterizationJNCI Journal of the National Cancer Institute, 1983
- Characterization of human colon carcinoma cell lines isolated from a single primary tumourBritish Journal of Cancer, 1983
- Natural history of hereditary cancer of the breast and colonCancer, 1982
- Characterization of WiDr: A human colon carcinoma cell lineIn Vitro Cellular & Developmental Biology - Plant, 1979
- CELL AND ORGAN-CULTURE TECHNIQUES APPLIED TO STUDY OF CARCINOMA OF COLON AND RECTUM1976
- Heredity and Adenocarcinoma of the ColonGastroenterology, 1967