Lack of antiscorbutic activity of ascorbate 2-sulfate in the rhesus monkey
Open Access
- 1 August 1976
- journal article
- research article
- Published by Elsevier in The American Journal of Clinical Nutrition
- Vol. 29 (8), 825-831
- https://doi.org/10.1093/ajcn/29.8.825
Abstract
Oral administration of 10 mg per kilogram of body weight of ascorbic acid (AA) completely prevented development of scurvy in juvenile rhesus monkey (Mucaca mulata) fed an AA-free liquid diet. The same dose cured scurvy when injected intramuscularly. An equimolar dose of ascorbic acid 2-sulfate (AA-2-S) did not prevent or cure scurvy. Neither AA nor AA-2-S altered serum cholesterol. AA but not AA-2-S reduced serum triglyceride. A case of scurvy in an AA-2-S treated monkey is described in detail.This publication has 8 references indexed in Scilit:
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