Studies on the Proteolytic and Antiproteolytic Activity of Blood Serum. I. Activation of Plasminogen with Trypsin.

Abstract

A fixed amt. of plasminogen inhibits a fixed amt. of trypsin; any remaining trypsin converts plasminogen to plasmin. It is assumed, not proved, that the enzymogen activated is plasminogen, the same substance that was studied and named by Christensen and MacLeod (Jour. Gen. Physiol. 28: 559. 1945) in their work on streptokinase.