The Differential Heritability of Regular Tobacco Use Based on Method of Administration
Open Access
- 1 February 2005
- journal article
- Published by Cambridge University Press (CUP) in Twin Research and Human Genetics
- Vol. 8 (1), 60-62
- https://doi.org/10.1375/twin.8.1.60
Abstract
Several large studies have demonstrated that the liability to smoke cigarettes is strongly genetically influenced. However, the role of genetic and environmental risk factors in the use of other common forms of tobacco use has yet to be studied. Data on the regular use of cigarettes, cigars, pipes, dip (moist snuff), and chewing tobacco from 2634 male twins were analyzed with ACE structural equation models. Twin similarity for regular cigarette and dip use was largely genetic in origin. However, twin resemblance for chewing tobacco was just about equally the result of genes and shared environment, and twin similarity for use of pipes and cigars was entirely the result of shared environmental factors. Thus, the genetic influences on the liability for regular tobacco use appear to vary based on tobacco type. The causes for the use of different forms of tobacco are complex and worthy of further study.Keywords
This publication has 15 references indexed in Scilit:
- Genetics of alcohol and tobacco use in humansAnnals of Medicine, 2003
- A meta‐analysis of estimated genetic and environmental effects on smoking behavior in male and female adult twinsAddiction, 2002
- Classical twin studies and beyondNature Reviews Genetics, 2002
- Twin studies of adult psychiatric and substance dependence disorders: are they biased by differences in the environmental experiences of monozygotic and dizygotic twins in childhood and adolescence?Psychological Medicine, 1998
- Parental treatment and the equal environment assumption in twin studies of psychiatric illnessPsychological Medicine, 1994
- Smoking and Major DepressionArchives of General Psychiatry, 1993
- A test of the equal-environment assumption in twin studies of psychiatric illnessBehavior Genetics, 1993
- Nicotine delivery kinetics and abuse liability.Journal of Consulting and Clinical Psychology, 1993
- A Population-Based Twin Study of Major Depression in WomenArchives of General Psychiatry, 1992
- Pharmacologic Aspects of Cigarette Smoking and Nicotine AddictionNew England Journal of Medicine, 1988