Uptake, Degradation, and Release of Fibrillar and Soluble Forms of Alzheimer's Amyloid β-Peptide by Microglial Cells
Open Access
- 1 November 1999
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 274 (45), 32301-32308
- https://doi.org/10.1074/jbc.274.45.32301
Abstract
No abstract availableKeywords
This publication has 62 references indexed in Scilit:
- Lysosomes Behave as Ca2+-regulated Exocytic Vesicles in Fibroblasts and Epithelial CellsThe Journal of cell biology, 1997
- RAGE and amyloid-β peptide neurotoxicity in Alzheimer's diseaseNature, 1996
- Evidence for nonvectorial, retrograde transferrin trafficking in the early endosomes of HEp2 cells.The Journal of cell biology, 1995
- Sorting of membrane components from endosomes and subsequent recycling to the cell surface occurs by a bulk flow process.The Journal of cell biology, 1993
- Inability to Detect β-Amyloid Protein Precursor mRNA in Alzheimer Plaque-Associated MicrogliaExperimental Neurology, 1993
- The carboxy terminus of the .beta. amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's diseaseBiochemistry, 1993
- Acute phase proteins but not activated microglial cells are present in parenchymal deposits in the brains of patients with hereditary cerebral hemorrhage with amyloidosis-Dutch typeNeuroscience Letters, 1992
- Differential APP gene expression in rat cerebral cortex, meninges, and primary astroglial, microglial and neuronal culturesFEBS Letters, 1991
- In-vitro matured human macrophages express Alzheimer's βA4-amyloid precursor protein indicating synthesis in microglial cellsFEBS Letters, 1991
- Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid proteinBiochemical and Biophysical Research Communications, 1984