Identity of rat kidney histidine-pyruvate aminotransferase with glutamine-oxo acid aminotransferase
- 1 January 1977
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 161 (1), 177-179
- https://doi.org/10.1042/bj1610177
Abstract
Histidine-pyruvate aminotransferase and glutamine-phenylpyruvate aminotransferase were purified from rat kidney by the same procedure. The ratio of the two activities remained constant during purification and was unchanged by a variety of treatments of the purified enzyme. Glutamine was found to act as a competitive inhibitor of histidine-pyruvate aminotransferase. These results suggest that rat kidney histidine-pyruvate aminotransferase is identical with glutamine-oxo acid aminotransferase. Identity of the two enzymes in other tissues of rats is discussed.This publication has 6 references indexed in Scilit:
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- Assays of glutamine and its aminotransferase with the enol-borate of phenylpyruvateArchives of Biochemistry and Biophysics, 1970