Abstract
Few of the physiological reactions which have been described as assay methods for the S sex hormones are precise enough to be valuable. The author reviews these methods, and other physiological reactions. He describes the preparation of [male] sex hormones from testis tissue and urine; proof of their chemical structure, relation of that structure to activity, and the possible origin of these substances in the body. Quantitative rela- tionships are especially stressed throughout the paper.