Scanning Electron Microscopic Observations of Surface Structure of Isolated Human Chromosomes
- 12 March 1971
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 171 (3975), 1024-1026
- https://doi.org/10.1126/science.171.3975.1024
Abstract
Isolated human chromosomes dried by the critical-point method have been assumed to retain their original three-dimensional shape when viewed under a transmission electron microscope. Our scanning electron microscopic study confirms this interpretation and reveals an appearance like that of a skein of yarn. The existence of fiber bridges between chromatid pairs and among chromosomes is demonstrated.Keywords
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