Eimeriosis in Cattle: Current Understanding

Abstract

This report addresses various aspects of the protozoan parasite Eimeria which contribute to their increasing recognition as important protozoal pathogens in cattle. Among others, questions of parasite biology and epidemiology, its impact on host physiology, and control strategies are dealt with. The tenacious oocysts are found ubiquitously in the environment making an infection of calves and young cattle, the most susceptible age group, almost inevitable. Further development, comprising of asexual multiplication, the merogony, and a subsequent sexual stage, the gamogony, takes place within cells of the small and large intestines, after which numerous unsporulated oocysts are formed and shed with the faeces. Of the more than a dozen species, Eimeria bovis and Eimeria zuernii only are made responsible for severe clinical disease characterized by haemorrhagic diarrhoea with sometimes fatal outcome. To a lesser extent, Eimeria alabamensis also can cause clinical disease. Because of the damage inflicted on the intestinal tissue, the digestive process and overall homeostasis can become severely affected, even with absence of clinical disease, with adverse effects on animal welfare and performance. The consequent economic losses for the cattle industry are thus substantial. Active (species specific) immunity, both humoral and cellular, develops rapidly after first antigen contact, its intensity being dependent on the number of oocysts ingested. However, no absolute protection is achieved and even older animals can excrete oocysts, contributing to a state of endemic stability. For efficient control, exact diagnosis of the Eimeria species involved and the evaluation of animal management and husbandry practices are of utmost importance. Mixed infections are the rule and only an occurrence of pathogenic species, together with clinical symptoms, justifies the assumption of a coccidiosis. Proper hygiene regime and ensuring unfavourable conditions for oocyst survival in the environment (cool and dry, disinfection procedures) will help to reduce infection pressure on the herd. Of the various pharmacological compounds used to treat coccidiosis, those which act against the late developmental stages, administered during prepatency (metaphylactically rather than therapeutically), are currently considered most effective.