Salbutamol as a Topical Anti-inflammatory Drug

Abstract

Using croton oil-induced rat ear edema, hydrocortisone and salbutamol show anti-inflammatory activity when applied topically. Both drugs act to some extent even when applied after the inflammation reaction is in progress. Both drugs are also active when applied to a shaven area of the back, a site remote from the ear inflammation. Salbutamol acts by a different mechanism than anti-inflammatory steroids. The advantages of salbutamol are discussed and it appears to be a useful adjunct in the treatment of inflammatory dermatoses.