AUTOÖXIDATION OF L-ASCORBIC ACID AND IMIDAZOLE NUCLEUS

Abstract

With a reaction mixture, containing 0.04[image] L-ascorbic acid, 5 x 10-4 [image] Fe++ and O2 (air) or L-ascorbic acid in the presence of 0.04[image] H2O2, the imidazole derivatives are degraded into amino acids accompanying the NH3-liberation, as follows: Imidazolecarboxylic acid[forward arrow] glycine; histidine [forward arrow]aspartic acid; imidazolepropionic acid[forward arrow] glutamic acid; urocanic acid[forward arrow]glutamic acid; methylimidazole[forward arrow] alanine; hydroxymethylimidazole[forward arrow]serine; histamine[forward arrow] unknown product with Rf-values of 0.65 and 0.25 with solvent mixtures of phenol-water and butanol-acetic acid-water, respectively.