TIME-LAPSE CINEMATOGRAPHY OF VANCOMYCIN-TREATED MICROBIAL CELLS
- 1 April 1967
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Microbiology
- Vol. 13 (4), 417-421
- https://doi.org/10.1139/m67-054
Abstract
The incubation of Bacillus subtilis W23 or Bacillus cereus on a vancomycin-containing medium resulted in a rapid contraction or shrinkage of the cells which was followed by lysis. The ejection of protoplasm from the cell during lysis was very forceful. The "burst" of protoplasmic material was observed at the ends of the cell and at one or two sites on the lateral cell wall. The results are consistent with the hypothesis that vancomycin inhibits cell wall synthesis and ultimately destroys the normal structure and integrity of the wall.This publication has 11 references indexed in Scilit:
- On the Initial Stage in Peptidoglycan Synthesis. Phospho-N-acetylmuramyl-pentapeptide Translocase (Uridine Monophosphate)*Biochemistry, 1966
- Vancomycin adsorption to Bacillus subtilis cell wallsArchives of Biochemistry and Biophysics, 1965
- LIPID-PHOSPHOACETYLMURAMYL-PENTAPEPTIDE AND LIPID-PHOSPHODISACCHARIDE-PENTAPEPTIDE: PRESUMED MEMBRANE TRANSPORT INTERMEDIATES IN CELL WALL SYNTHESISProceedings of the National Academy of Sciences, 1965
- EFFECT OF VANCOMYCIN ON THE SYNTHESIS OF THE CELL WALL AND CYTOPLASMIC MEMBRANE OF STAPHYLOCOCCUS AUREUSCanadian Journal of Microbiology, 1965
- The Synthesis of Teichoic AcidsPublished by Elsevier ,1964
- Effect of vancomycin on Bacillus subtilisArchives of Biochemistry and Biophysics, 1964
- SYNTHESIS OF TEICHOIC ACIDS .I. POLYGLYCEROPHOSPHATE1964
- INHIBITION OF MICROBIAL GROWTH AND SEPARATION BYd-SERINE, VANCOMYCIN, AND MITOMYCIN CJournal of Bacteriology, 1963
- INHIBITION BY ANTIBIOTICS OF THE GROWTH OF BACTERIAL AND YEAST PROTOPLASTSJournal of Bacteriology, 1962