A Human Physiologically-Based Model for Glycyrrhzic Acid, A Compound Subject to Presystemic Metabolism and Enterohepatic Cycling
- 1 January 2000
- journal article
- clinical trial
- Published by Springer Nature in Pharmaceutical Research
- Vol. 17 (12), 1516-1525
- https://doi.org/10.1023/a:1007661209921
Abstract
Purpose. To analyze the role of the kinetics of glycyrrhizic acid (GD) in its toxicity. A physiologically-based pharmacokinetic (PBPK) model that has been developed for humans. Methods. The kinetics...Keywords
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