A Spectroscopic Investigation of Hydrogen Bond Patterns in Crystalline and Amorphous Phases in Dihydropyridine Calcium Channel Blockers
- 1 January 2002
- journal article
- research article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 19 (4), 477-483
- https://doi.org/10.1023/a:1015147729564
Abstract
Purpose. To gain insight into the molecular structure of amorphous compounds by investigating hydrogen bonding patterns and strength in a series of structurally related compounds. Seven 1,4-dihydro-...Keywords
This publication has 9 references indexed in Scilit:
- Sugar–polymer hydrogen bond interactions in lyophilized amorphous mixturesJournal of Pharmaceutical Sciences, 1998
- Binary System of (R)- and (S)-Nitrendipine—Polymorphism and StructureJournal of Pharmaceutical Sciences, 1997
- Rational Design of Stable Lyophilized Protein Formulations: Some Practical AdvicePharmaceutical Research, 1997
- Spectroscopic Characterization of Interactions Between PVP and Indomethacin in Amorphous Molecular DispersionsPharmaceutical Research, 1997
- Structure of the calcium channel antagonist, nimodipineActa Crystallographica Section C Crystal Structure Communications, 1989
- Crystal structures and pharmacologic activities of 1,4-dihydropyridine calcium channel antagonists of the isobutyl methyl 2,6-dimethyl-4-(substituted phenyl)-1,4-dihydropyridine-3,5-dicarboxylate (nisoldipine) seriesJournal of Medicinal Chemistry, 1988
- Evidence for Solid- and Liquid-State Interactions in a Furosemide-Polyvinylpyrrolidone Solid DispersionJournal of Pharmaceutical Sciences, 1987
- Crystal structure of the dihydropyridine calcium antagonist felodipine. Dihydropyridine binding prerequisites assessed from crystallographic dataJournal of Medicinal Chemistry, 1986
- Crystal structures of calcium channel antagonists: 2,6-dimethyl-3,5-dicarbomethoxy-4-[2-nitro-, 3-cyano-, 4-(dimethylamino)-, and 2,3,4,5,6-pentafluorophenyl]-1,4-dihydropyridineJournal of Medicinal Chemistry, 1980