Heterodimeric Phosphoinositide 3-Kinase Consisting of p85 and p110β Is Synergistically Activated by the βγ Subunits of G Proteins and Phosphotyrosyl Peptide
Open Access
- 1 September 1997
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 272 (39), 24252-24256
- https://doi.org/10.1074/jbc.272.39.24252
Abstract
No abstract availableKeywords
This publication has 31 references indexed in Scilit:
- A Target of Phosphatidylinositol 3,4,5‐Trisphosphate with a Zinc Finger Motif Similar to that of the ADP‐Ribosylation‐Factor GTPase‐Activating Protein and Two Pleckstrin Homology DomainsEuropean Journal of Biochemistry, 1997
- Phosphatidylinositol 3-Kinase Is an Early Intermediate in the Gβγ-mediated Mitogen-activated Protein Kinase Signaling PathwayJournal of Biological Chemistry, 1996
- Radiolabeling of Catalytic Subunits of PI 3-Kinases with 17β-Hydroxy-16α-(125I)Iodowortmannin: Identification of the Gβγ-Sensitive Isoform as a Complex Composed of 45- and 100-kDa SubunitsBiochemical and Biophysical Research Communications, 1995
- Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinaseTrends in Biochemical Sciences, 1995
- G Protein-coupled Chemoattractant Receptors Regulate Lyn Tyrosine Kinase·Shc Adapter Protein Signaling ComplexesPublished by Elsevier ,1995
- Sequestration of a G-protein βγ Subunit or ADP-ribosylation of Rho Can Inhibit Thrombin-induced Activation of Platelet Phosphoinositide 3-KinasesPublished by Elsevier ,1995
- Regulation of Phosphatidylinositol 3′-Kinase by Tyrosyl PhosphoproteinsPublished by Elsevier ,1995
- Structure, regulation and function of phosphoinositide 3-kinasesBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1994
- Structure of 85 kDa Subunit of Human Phosphatidylinositol 3‐Kinase Analyzed by Using Monoclonal AntibodiesJapanese Journal of Cancer Research, 1993
- Phosphatidylinositol 3-kinase: Structure and expression of the 110 kd catalytic subunitCell, 1992