OBSERVATIONS INDICATING ABSENCE OF GLOMERULAR INTERMITTENCE IN NORMAL DOGS AND RABBITS

Abstract

Observations on glomerular perfusion were made on 17 kidneys of lldogs and on 13 kidneys of 7 rabbits following inj. of a C suspension into the renal artery. Some of the animals were deprived of food and water for 24 hrs. preceding the expt. All glomeruli were injected, or the distr. of injected and uninjected was such as to favor the interpretation that failure of inj. was due to manner of distr. of ink in the larger preglomerular vessels rather than to closure of the glomeruli or of their afferent arterioles. Under conditions normally encountered the mammalian kidney shows all of its glomeruli'' open all of tne time; the possibility that extreme conditions, as severe hemorrhage or sudden increments of circulating epinephrin, may bring on intermittence in the mammal is not excluded.