Response of Guinea Pigs to Diets Deficient in Choline.

Abstract

7 choline-deficient diets were fed to young rats and guinea pigs. While each resulted in fatty liver formation in the rats, in no instance was there observed an appreciable accumulation of fat in the guinea pig livers. This fact was correlated with the lack of hepatic choline oxi-dase activity in the guinea pig as compared to all spp. which have, to date,been found susceptible to dietary choline deficiency.