Imipenem Resistance in Salmonella enterica Serovar Wien Related to Porin Loss and CMY-4 β-Lactamase Production
Open Access
- 1 March 2003
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 47 (3), 1165-1168
- https://doi.org/10.1128/aac.47.3.1165-1168.2003
Abstract
Two multidrug-resistant Salmonella enterica serovar Wien strains (SW468 and SW1107) were isolated in 2001 in Tunis. Both strains produced the β-lactamases TEM-1, SHV-2a, and CMY-4, whereas strain SW1107 also produced the β-lactamase CTX-M-3. The imipenem-resistant strain (SW468) was totally devoid of the OmpF-immunorelated porin. Imipenem resistance was shown as being related to porin loss and CMY-4 β-lactamase production.Keywords
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