The Reaction of Enaminones with Carboxamidines: A Convenient Route for the Synthesis of Polyaza Heterocycles

Abstract

A simple and efficient synthetic method to polyaza heterocyclic structures containing 1,3-pyrimidine units has been developed. It is based on the reaction of the enaminones such as 5, 7 and 9 with the appropriate carboxamidines under basic conditions. By this procedure several new polyaza heterocycles have been prepared in good yields.