Crossing-Over and the Centromere
- 1 January 1967
- journal article
- research article
- Published by S. Karger AG in Cytogenetic and Genome Research
- Vol. 6 (5), 331-341
- https://doi.org/10.1159/000154937
Abstract
Experiments with human lymphocytes and H.Ep.2 human neoplastic cells treated with tritiated thymidine yielded evidence which suggests that sister chromatid crossing-over may occur in the centromere. As a result of this study a possible mechanism of isochromosome formation is postulated.Keywords
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