An Approach to the Control of Massive Hemorrhage in Cyclophosphamide-Induced Cystitis by Intravenous Vasopressin: A Case Report

Abstract
Massive bleeding due to cyclophosphamide-induced [bone-marrow tumor therapy] hemorrhagic cystitis [in a human] was not affected by intravesical instillation of 4% formalin or 1% silver nitrate. After initiation of a continuous systemic infusion of vasopressin, hematuria and transfusion requirements diminished markedly. Adverse reactions were mild. I.v. vasopressin was a safe and effective means to control temporarily threatening hemorrhagic cystitis.