SOME OBSERVATIONS ON THE EFFECT OF HISTAMINE, 48/80 AND FIVE ANTIHISTAMINIC DRUGS OF THE SURVIVAL TIME OF ORTHOTOPIC SKIN HOMOGRAFTS IN THE MOUSE

Abstract

Fa a study of the effect of histamine, a histamine release agent (48/80) and five anti-histamines (triprolidine HCl, chlorcycEzine HCL mepyramine maleate, promethazine HCl and chlorpheniramine HCl) on the survival time of orthotopic first-set skin homografts in the mouse (A donor, CBA host) it has been shown that the increase observed was as great in the saline controls as in the drug treated animals.