NEONATAL GLOMERULONEPHRITIS AND NEPHROTIC SYNDROME IN A 1,320-GM. PREMATURELY BORN INFANT

Abstract

ALTHOUGH the nephrotic syndrome in glomerulonephritis is common in early childhood, its occurrence in the neonatal period is extremely rare and, so far as we have been able to determine, has not been described in the literature in the newly born premature infant. In 1930, Mitchell¹reviewed the literature on congenital nephritis and nephritis in the newborn infant and found a few cases in the foreign literature before or at the turn of the century. Lapage,²in 1932, reported a case of "hemorrhagic nephritis" in an 11-day-old full-term boy. The autopsy did not show glomerulonephritis. Conrad,³in 1938, reported three cases of neonatal nephritis in full-term infants, with one death. No autopsy was obtained, and therefore the type of nephritis was not determined. Montagna and Ausberg,⁴in 1942, reported the case of a full-term boy dying on the 18th day with a clinical diagnosis of glomerulonephritis.