Transformation of Rabbit Lymphocytes by Specific Antigens.
- 1 August 1967
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 125 (4), 1305-1308
- https://doi.org/10.3181/00379727-125-32342
Abstract
Lymphocytes from the blood of rabbits immunized with extracts of bovine or rat heart or with human IgG [immunoglobulin G], reacted in vitro when cultured with the specific antigen. The reaction consisted of intense blast transformation, mitotic activity and incorporation of H3-thymidine. The level of response was dose-dependent. Some unstimulated (control) cultures showed moderate "spontaneous" blast formation, without, however, mitotic activity or thymidine uptake.This publication has 10 references indexed in Scilit:
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