PULMONARY FUNCTION IN THE NEWBORN INFANT. V. TRAPPED GAS IN THE NORMAL INFANT'S LUNG*
Open Access
- 1 December 1963
- journal article
- research article
- Published by American Society for Clinical Investigation in JCI Insight
- Vol. 42 (12), 1850-1857
- https://doi.org/10.1172/jci104869
Abstract
Total thoracic gas volume (TGV) and its ventilated component, the functional residual capacity (FRC) have been measured concurrently in 23 normal newborn infants; TGV was measured by a plethysmographic technique based on Boyle''s Law and FRC was measured by nitrogen dilution. TGV was significantly larger than FRC in 10 babies, indicating the presence of a very poorly ventilated portion of lung amounting to 25 to 60% of the total TGV. This poorly ventilated gas is probably trapped in terminal lung units that are intermittently nonventilated, especially during quiet breathing.Keywords
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