Ketoconazole treatment of chronic mucocutaneous candidiasis
- 1 October 1980
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Dermatology
- Vol. 116 (10), 1137-1141
- https://doi.org/10.1001/archderm.116.10.1137
Abstract
Five patients received ketoconazole treatment of chronic mucocutaneous candidiasis. One also had disseminated histoplasmosis and cryptococcosis. Ketoconazole was well absorbed after an oral dose of 200 mg and produced detectable anti-fungal blood levels for > 8 h after each dose. Thrush cleared in < 2 wk in all patients. Cutaneous lesions cleared slowly during several months of treatment. A patient with polymycotic infection had a rapid clearing of candidiasis but her histoplasmosis did not respond to 3 wk of treatment. Adverse drug effects were minimal. Ketoconazole is a promising new agent for the treatment of chronic mucocutaneous candidiasis.This publication has 10 references indexed in Scilit:
- Suppression of Cryptococcosis and Histoplasmosis by Ketoconazole in Athymic Nude MiceThe Journal of Infectious Diseases, 1980
- Treatment of Chronic Oral Candidiasis with Clotrimazole TrochesNew England Journal of Medicine, 1978
- Oral Therapy for Experimental Coccidioidomycosis with R41 400 (Ketoconazole), a New Imidazole1,2American Review of Respiratory Disease, 1978
- Comparison of the in Vitro Antifungal Activities of Miconazole and a New Imidazole, R41,400The Journal of Infectious Diseases, 1978
- COCCIDIOIDOMYCOSIS .1.Published by Elsevier ,1978
- Miconazole in the treatment of chronic mucocutaneous candidiasis: A preliminary reportThe Journal of Pediatrics, 1977
- ClotrimazoleAmerican Journal of Diseases of Children, 1977
- MICONAZOLE IN TREATMENT OF SYSTEMIC FUNGAL INFECTIONSPublished by Elsevier ,1977
- Chronic mucocutaneous candidosis: A reviewMycopathologia, 1976
- Chronic Mucocutaneous Candidiasis: Model-Building in Cellular ImmunityAnnals of Internal Medicine, 1971