Urinary Excretion of theN-Acetyl Cysteine Conjugate of Cis-1,3-Dichloropropene by Exposed Individuals
- 1 July 1984
- journal article
- research article
- Published by Taylor & Francis in Archives of environmental health
- Vol. 39 (4), 271-275
- https://doi.org/10.1080/00039896.1984.10545848
Abstract
A gas chromatographic-mass spectrometric assay was developed to identify and measure the N-acetyl cysteine conjugate of cis-1,3-dichloropropene. The assay was used to show that individuals exposed to 1,3-dichloropropene vapor during field applications excrete this conjugate in their urine. The recoveries of the conjugate were correlated with the product of airborne concentrations and the duration of exposure (r = 0.83).This publication has 3 references indexed in Scilit:
- Glutathione conjugation in the detoxication of (Z)-1,3-dichloropropene (a component of the nematocide D-D) in the ratXenobiotica, 1979
- The toxicity of 1,3-dichloropropene as determined by repeated exposure of laboratory animalsAihaj Journal, 1977
- The excretion and retention of components of the soil fumigant D-D and their metabolites in the ratFood and Cosmetics Toxicology, 1971