Differentiation of Parathyroid Hyperplasia from Adenoma

Abstract

The development of the technic of radioimmunoassay for the detection of peptide hormones in blood by Berson and Yalow¹ must rank as one of the major advances in endocrine physiology and clinical endocrinology. Its development has allowed us to expand considerably our knowledge of how hormonal secretion is controlled, and how the different hormones interact in regulating metabolism. It has, as well, given the clinician an extremely important and highly accurate tool with which to define the pathogenesis of various endocrinopathies. The immunoassay of insulin, growth hormone and a number of other peptide hormones has now become a matter of . . .