Laminin A-related domains in crb protein ofDrosophilaand their possible role in epithelial polarization
- 2 September 1991
- journal article
- Published by Wiley in FEBS Letters
- Vol. 289 (1), 99-101
- https://doi.org/10.1016/0014-5793(91)80917-r
Abstract
It is shown that four domains of the integral membrane protein crb of Drosophila are homologous with five C-terminal domains of the laminin A chain and merosin. Since the latter domains of laminin A have been implicated in determining epithelial polarity, the homology may suggest a similar function for these domains or crb. Such a function would be consistent with the known importance of crb for organization of epithelia in DrosophilaKeywords
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