A sequential study of the relationship between faecal Klebsiella aerogenes and the common clinical manifestations of ankylosing spondylitis.
Open Access
- 1 February 1982
- journal article
- research article
- Published by BMJ in Annals Of The Rheumatic Diseases
- Vol. 41 (1), 15-20
- https://doi.org/10.1136/ard.41.1.15
Abstract
An 8-month sequential study at 4-weekly intervals of faecal Klebsiella aerogenes and clinical activity of ankylosing spondylitis is described. Similar frequencies of faecal K. aerogenes were found in the 44 patients and 36 healthy controls studied. Eighteen patients on 19 occasions had K. aerogenes cultured from their faeces, when the preceding specimen had been negative. Six (31.6%) of these occasions were associated with a deterioration in clinical state compared with a similar deterioration associated with only 17 (9.8%) of the remaining 174 faecal culture sequences (p less than 0.02). These results suggest that clinical deterioration in ankylosing spondylitis may be associated with the acquisition of faecal K. aerogenes.This publication has 13 references indexed in Scilit:
- Faecal carriage of klebsiella by patients with ankylosing spondylitis and rheumatoid arthritis.Annals Of The Rheumatic Diseases, 1980
- An investigation into the incidence and sources of klebsiella infections in hospital patientsEpidemiology and Infection, 1979
- Klebsiella pneumoniae and acute anterior uveitis in ankylosing spondylitis.BMJ, 1979
- Klebsiella pneumoniae.Annals Of The Rheumatic Diseases, 1978
- Sequential studies in ankylosing spondylitis. Association of Klebsiella pneumoniae with active disease.Annals Of The Rheumatic Diseases, 1978
- Discordance for ankylosing spondylitis in monozygotic twins.Annals Of The Rheumatic Diseases, 1977
- ANKYLOSING SPONDYLITIS: KLEBSIELLA AND HL-A B27Rheumatology, 1977
- High Association of an HL-A Antigen, W27, with Ankylosing SpondylitisNew England Journal of Medicine, 1973
- ANKYLOSING SPONDYLITIS AND HL-A 27The Lancet, 1973
- Genetics of ankylosing spondylitis.Journal of Medical Genetics, 1967