γ‐Glutamyl Transpeptidase: Catalytic Mechanism and Gene Expression
- 1 January 1998
- book chapter
- Published by Wiley in Advances in enzymology and related areas of molecular biology
- Vol. 72, 239-278
- https://doi.org/10.1002/9780470123188.ch7
Abstract
Introduction Structural and Topological Features of γ-Glutamyl Transpeptidase Biosynthesis and Processing of γ-Glutamyl Transpeptidase Role of γ-Glutamyl Transpeptidase in Glutathione Metabolism Reactions Catalyzed by γ-Glutamyl Transpeptidase and Substrate Specificity Active site of γ-Glutamyl Transpeptidase γ-Glutamyl Transpeptidase-Related Enzyme and γ-Glutamyl Transpeptidase Transcripts Unique to Human Lung Gene Structure and Expression Cancer-Associated Changes of γ-Glutamyl Transpeptidase ConclusionThis publication has 124 references indexed in Scilit:
- Crystallization and Preliminary X-ray Analysis of γ-Glutamyltranspeptidase from Escherichia coli K-12Journal of Molecular Biology, 1993
- Repetitive 5-azacytidine treatments of Fao cells induce a stable and strong expression of gamma-glutamyl transpeptidaseJournal of Cellular Physiology, 1992
- Different gamma-glutamyl transpeptidase mRNAs are expressed in human liver and kidneyBiochemical and Biophysical Research Communications, 1989
- Expression of rat renal gamma — glutamyltransferase cDNA in Escherichia coliBiochemical and Biophysical Research Communications, 1989
- In vitro translation and processing of human hepatoma cell (Hep G2) γ-glutamyl transpeptidaseBiochemical and Biophysical Research Communications, 1988
- The conversion of the precursor form of γ-glutamyltranspeptidase to its subunit form takes place in brush border membranesBiochemical and Biophysical Research Communications, 1983
- The binding mechanism of glutathione and the anti-tumor drug L-(αS.5S)-α-amino-3-chloro-4.5-dihydro-5-isoxazoleacetic acid (AT-125; NSC-163501) to γ-glutamyltransferaseBiochemical and Biophysical Research Communications, 1983
- Gamma-glutamyltransferase activity of liver plasma membrane: Induction following chronic alcohol consumptionBiochemical and Biophysical Research Communications, 1981
- Inactivation of γ-glutamyl transpeptidase by phenylmethanesulfonyl fluoride, a specific inactivator of serine enzymesBiochemical and Biophysical Research Communications, 1978
- Hydrolysis and transfer reactions catalyzed by γ-glutamyl transpeptidase; Evidence for separate substrate sites and for high affinity of L-cystineBiochemical and Biophysical Research Communications, 1976