In Vitro Studies on Mechanism of Action of Thyrotropin Releasing Factor
- 1 February 1968
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 127 (2), 488-490
- https://doi.org/10.3181/00379727-127-32722
Abstract
The TSH [thyroid stimulating hormone] secretion from [rat] hemipituitary glands is stimulated in vitro by TRF and this action is blocked by large doses of L-thyroxine. The response to TRF is inhibited by both 2,4-dinitrophenol and oligo-mycin, indicating that energy is required for TRF action. It is not inhibited by cyclohexamide or ouabain.This publication has 5 references indexed in Scilit:
- Immunoassay Studies of Thyrotropin in Rat Pituitary Glands and SerumEndocrinology, 1967
- Competition Between Thyroxine and TRF at the Pituitary Level in the Release of TSH.Experimental Biology and Medicine, 1967
- Enzymatic Basis for Active Transport of Na+ and K+ Across Cell MembranePhysiological Reviews, 1965
- Effects of Thyroidectomy and Thyroxine on Hypothalamic Concentration of ‘Thyrotropin Releasing Factor’ and Pituitary Content of Thyrotropin in RatsNeuroendocrinology, 1965
- In VitroSecretion of Thyrotropin (TSH): Stimulation by a Hypothalamic Peptide (TRF)Endocrinology, 1963