The Response to Artificial Selection Due to Autosomal Genes of Large Effect III. The Effects of Linkage on the Rate of Advance and Approach to Fixation in Finite Populations

Abstract

The effects of linkage on the total response to artificial selection in finite populations have been discussed in the second paper of this series, making use of a simple genetic model involving two identical loci of additive effect. In the present paper the following related parameters are discussed: (1) the initial rate of response; (2) the half-life and 0·95 life of the selection process; (3) the number of generations to 50 and 95% fixation; (4) the mean coefficient of linkage disequilibrium; and (5) the coefficient of joint segregation.