Purification and partial characterization of human lymphoblast interferon.
- 1 November 1979
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 76 (11), 5601-5605
- https://doi.org/10.1073/pnas.76.11.5601
Abstract
One component of human lymphoblastoid interferon [a potential antitumor and antiviral agent] obtained from Namalwa cultures induced by Newcastle disease virus was purified to a specific activity of 2.5 .times. 108 interferon units/mg of protein (protein content based on amino acid analysis). A single polypeptide species with an apparent MW of 18,500 comigrating with the antiviral [vesicular stomatitis virus] activity was observed by sodium dodecyl sulfate/polyacrylamide gel electrophoresis. Preliminary amino-terminal sequencing results suggest that the interferon species is essentially homogeneous.This publication has 29 references indexed in Scilit:
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