A and B and A1Leb Substances in Glycosphingolipid Fractions of Human Serum1
- 1 January 1975
- journal article
- Published by Wiley in Vox Sanguinis
- Vol. 28 (1), 25-33
- https://doi.org/10.1111/j.1423-0410.1975.tb02737.x
Abstract
A and B and A1Leb substances were adsorbed onto red cells exposed to glycosphingolipid fractions prepared from the serum of group A and B and A1,Le(a minus b plus) donors. Group O cells exposed to fractions prepared from the serum of group A or B donors were agglutinated by an IgM cross-reacting antibody present in some group O sera. Cells exposed to fractions from A1,Le(a minus b plus) serum were agglutinated by anti-A1Leb. The amount of A substance in the fractions was related to the A subtype (A1 or A2) and to the Lewis and secretor phenotype of the donor. The uptake of blood-group substances from the lipid fractions was inhibited by the addition of whole serum to the fractions.Keywords
This publication has 17 references indexed in Scilit:
- ‘True’ Genotype of Chimeric Twins Revealed by Blood‐group Gene Products in PlasmaVox Sanguinis, 1974
- The Effect of Elution on the Reactivity of Antibodies of the ABO System, Including Cross-reacting Antibodies, as Demonstrated by Use of Red Cells of Various Subgroups of A, and Group BBritish Journal of Haematology, 1974
- Haptenic Relationship between Bovine J, Human A, and Porcine A Blood Group Systems Tested with Lipids and Nonlipid Fractions of BloodVox Sanguinis, 1973
- Detection of Cytotoxic Non‐HL‐A AntiseraVox Sanguinis, 1972
- The J Substance of CattleVox Sanguinis, 1971
- LEWIS SUBSTANCES IN A HUMAN MARROW-TRANSPLANTATION CHIMÆRAThe Lancet, 1971
- HUMAN BLOOD CHIMqRA WITH SEEMING BREAKDOWN OF IMMUNE TOLERANCEThe Lancet, 1970
- The J Blood-Group Substance of Cattle. J Haptenic Activity of Glycosphingolipids of SerumEuropean Journal of Biochemistry, 1970
- Siedler: An Antibody which Reacts with A1Le(a‐b+) Red CellsVox Sanguinis, 1968
- Blood Chimerism in a Pair of TwinsBMJ, 1957