The action of polyhydric phenols on urease; the influence of thiol compounds

Abstract

The following compounds are arranged in the order of their decreasing toxicity for urease: quinol, catechol, gallic acid and pyrogallol, adrenalin and protocatechuic acid. Resorcinol and phloroglucinol were non-toxic. The toxicity of catechol or quinol at concs. as low as 1/100,000 was not affected by the presence of KCN or ammo-acids. Thiol compounds and Na hydrosulphite decreased or eliminated the toxicity of polyhydric phenols to urease. H2O2 and "''hyperol" were very toxic to urease but not so markedly so as quinol. Quinone was more toxic than quinol.