Directed ortho Metalation - Cross Coupling Connections. Nickel (0) - Catalyzed Cross Coupling of Aryl Triflates with Organozinc Reagents

Abstract

Aryl zinc reagents, derived by directed ortho metalation, undergo cross coupling with aryl triflates under Ni(0) catalysis to provide a general, regiospecific method for the synthesis of diverse functionalized biaryls (Table).