Thermoanalytical and histological study of intra-articular papain-induced degradation and repair of rabbit cartilage. II. Mature animals.
Open Access
- 1 February 1976
- journal article
- research article
- Published by BMJ in Annals Of The Rheumatic Diseases
- Vol. 35 (1), 23-26
- https://doi.org/10.1136/ard.35.1.23
Abstract
The effect of papain treatment on the cartilage tissue of the knee joint of mature rabbits was studied by histological and thermoanalytical methods. Changes taking place in the composition of cartilage in the course of ageing were shown. As a result of papain treatment a significant irreversible destruction of the ground substance took place. Papain-induced loss of proteoglycans and the intensity of repair reactions and age-related differences are discussed.This publication has 6 references indexed in Scilit:
- Thermoanalytical and histological study of intra-articular papain-induced degradation and repair of rabbit cartilage. I. Immature animals.Annals Of The Rheumatic Diseases, 1974
- Biochemical and metabolic abnormalities in osteoarthritic human cartilage.1973
- Papain-induced degenerative arthritis of the hip in rabbits.1971
- Thermoanalytical assay of glycosaminoglycans.1971
- The Experimental Production of Arthritis: A ReviewAnnals Of The Rheumatic Diseases, 1960
- Der DerivatographAnalytical and Bioanalytical Chemistry, 1958