Clinical ventilation-perfusion scintigraphy
- 1 August 1981
- journal article
- review article
- Published by Wiley in Clinical Physiology and Functional Imaging
- Vol. 1 (4), 323-338
- https://doi.org/10.1111/j.1475-097x.1981.tb00901.x
Abstract
Ventilation-perfusion scintigraphy is an established procedure for the investigation of lung disease. Perfusion scans are commonly obtained with a gamma-camera following injection of 99mTc-labelled microspheres. For the assessment of regional lung ventilation, a number of techniques are now being employed, i.e. 133Xe and 127Xe single breath/washout studies, continuous inhalation of 81mKr and inhalation of radioactive aerosols. The latter two methods are now gaining consideration in clinical practice. Lung perfusion scanning is highly sensitive for detection of regional abnormalities of blood flow; the diagnosis of pulmonary embolism remains the most important clinical application of the technique. In this context, the use of a ventilation scan is required in order to increase the specificity of the procedure. In general, lung ventilation-perfusion scintigraphy is of great value for the management of patients with both primary lung disease and heart disease, by providing pathophysiological information of importance for the diagnosis, follow up and the functional evaluation of the patient.Keywords
This publication has 54 references indexed in Scilit:
- A comparative analysis of pulmonary perfusion scans with pulmonary angiogramsAmerican Heart Journal, 1976
- Radioisotope measurements of regional lung function in bronchogenic carcinomaThe British Journal of Radiology, 1975
- Assessment of regional ventilation by continuous inhalation of radioactive krypton-81m.BMJ, 1975
- The measurement of regional ventilation during tidal breathing: a comparison of two methods in healthy subjects, and patients with chronic obstructive lung diseaseThe British Journal of Radiology, 1975
- The Complementary Roles of Chest Radiography, Lung Scanning, and Selective Pulmonary Angiography in the Diagnosis of Pulmonary EmbolismCirculation, 1974
- The role of lung imaging in pulmonary embolismPublished by Oxford University Press (OUP) ,1973
- Distribution of Pulmonary Blood Flow after Myocardial Ischemia and InfarctionCirculation, 1970
- Regional Ventilation in the Differential Diagnosis of Pulmonary EmbolismCirculation, 1969
- Assessment of Pulmonary Photoscanning and Angiography in Experimental Pulmonary EmbolismCirculation, 1969
- Alterations in Regional Pulmonary Blood Flow in Mitral Valve Disease Studied by Radioisotope ScanningCirculation, 1966