Strain Differences During Intraventricular Infusion of Norepinephrine: Possible Role of Receptor Sensitivity
- 25 July 1975
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 189 (4199), 301-303
- https://doi.org/10.1126/science.1145205
Abstract
Two rat strains previously shown to differ with respect to behavioral activity, regional brain tyrosine hydroxylase activity, and norepinephrine-elicited accumulation of adenosine 3', 5'-monophosphate exhibited differential behavioral responsiveness during the intraventricular infusion of norepinephrine. The results are interpreted in terms of differential catecholamine receptor sensitivity.Keywords
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