The dissociation of Q-beta-replicase and the relation of one of the components to a poly-C-dependent poly-G-polymerase.
- 1 June 1967
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 57 (6), 1833-1840
- https://doi.org/10.1073/pnas.57.6.1833
Abstract
Experiments demonstrate that Q[beta]-replicase can be separated into a "heavy" and a "light" component in sucrose gradients. The heavy is about 130,000 and the light 80,000 in molecular weight. In isolation, neither component can initiate the reaction when challenged with intact normal Q[beta]-RNA. Full activity is reconstituted in a mixture of the 2. The heavy component can synthesize poly G if poly C is provided as a template.This publication has 16 references indexed in Scilit:
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