Anticonvulsant Properties of Hydroxylamine and Elevation of Cerebral -Aminobutyric Acid in Cats.
- 1 August 1959
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 101 (4), 815-817
- https://doi.org/10.3181/00379727-101-25106
Abstract
Hydroxylamine when administered to immobilized cats in acute experiments in doses of 10-20 mg/kg markedly reduced the duration and spread of electrically induced after-discharges while increasing cerebral levels of gamma-aminobutyric acid. These findings increase the probability that a causal relationship may exist between the metabolism of gamma-aminobutyric acid in a particular cerebral area and its excitability.Keywords
This publication has 3 references indexed in Scilit:
- Elevation of -Aminobutyric Acid in Rat Brain with Hydroxylamine.Experimental Biology and Medicine, 1959
- CONVULSANT HYDRAZIDES .2. COMPARISON OF ELECTRICAL CHANGES AND ENZYME INHIBITION INDUCED BY THE ADMINISTRATION OF THIOSEMICARBAZIDE1957
- CONVULSANT HYDRAZIDES .1. INVITRO AND INVIVO INHIBITION OF VITAMIN-B6 ENZYMES BY CONVULSANT HYDRAZIDES1957