Purification of thymus mRNA coding for a 16,000-dalton polypeptide containing the thymosin alpha 1 sequence.
Open Access
- 1 January 1981
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 78 (1), 192-195
- https://doi.org/10.1073/pnas.78.1.192
Abstract
A mRNA fraction purified by preparative polyacrylamide disc gel electrophoresis from calf thymus polysomes codes for a polypeptide(s) having a mass of 16,000-17,000 daltons. This polypeptide contains amino acid sequences corresponding to residues 11-18 and 19-25 of thymosin .alpha.1. The yield of octapeptide indicates that the 16,000 dalton peptide is the major product formed in the cell-free synthesis system containing the purified mRNA.Keywords
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