Immunofluorescence Evidence for the Distribution of Cyclic AMP in Cells and Cell Masses of the Cellular Slime Molds
- 1 May 1974
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 71 (5), 1623-1625
- https://doi.org/10.1073/pnas.71.5.1623
Abstract
With immunofluorescent techniques it has been possible to show that bound cyclic AMP is uniformly distributed in the nucleus and cytoplasm of a number of species of cellular slime molds. One species (which does not respond to cyclic AMP as an acrasin) is an exception and has its cyclic AMP concentrated in the nucleus during the feeding and aggregation stage. In cell masses of Dictyostelium discoideum that show early signs of differentiation the anterior, prestalk cells contain more cyclic AMP than the posterior, prespore cells.Keywords
This publication has 6 references indexed in Scilit:
- A Cell-Contact Model for Cellular Position Determination in DevelopmentProceedings of the National Academy of Sciences, 1973
- A METHOD FOR DETECTING INTRACELLULAR CYCLIC ADENOSINE MONOPHOSPHATE BY IMMUNOFLUORESCENCEJournal of Histochemistry & Cytochemistry, 1972
- Induction of Stalk Cell Differentiation by Cyclic AMP in the Cellular Slime Mold Dictyostelium discoideumProceedings of the National Academy of Sciences, 1970
- Synthesis of Cyclic AMP in Dictyostelium discoideum and Polysphondylium pallidumNature, 1969
- Adenosine-3′,5′-Phosphate: Identification as Acrasin in a Species of Cellular Slime MoldScience, 1969
- RADIOIMMUNOASSAY FOR THE MEASUREMENT OF ADENOSINE 3′,5′-CYCLIC PHOSPHATEProceedings of the National Academy of Sciences, 1969