Autoradiographische Untersuchungen über das Verhalten der Desoxyribonucleinsäure in Herpesvirus-infizierten Zellen
Open Access
- 1 March 1963
- journal article
- research article
- Published by Walter de Gruyter GmbH in Zeitschrift für Naturforschung B
- Vol. 18 (3), 211-215
- https://doi.org/10.1515/znb-1963-0307
Abstract
In the nuclei of HeLa cells infected with Herpes simplex virus which before infection had H3-thymidine incorporated in their DNA, marking was found in the periphery, in the so-called border chromatin. H3 -thymidine added after infection was taken up only in the inner part of the nucleus. The border chromatin remained free. This indicates that the DNA-metabolism characteristic for the cell was interrupted and now a DNA-metabolism for the reproduction of the virus occurs only in the inner part of the nucleus.This publication has 7 references indexed in Scilit:
- Biochemistry of vaccinia-infected mouse fibroblasts (strain L-M)Virology, 1962
- Biochemistry of vaccinia-infected mouse fibroblasts (strain L-M)Virology, 1962
- Quantitative cytological studies on Hela cells infected with herpes virusVirology, 1961
- DNA synthesis in individual L-strain mouse cellsBiochimica et Biophysica Acta, 1959
- ELECTRON MICROSCOPIC OBSERVATIONS ON THE DEVELOPMENT OF HERPES SIMPLEX VIRUSThe Journal of Experimental Medicine, 1959
- Changes in nucleic acid content of HeLa cells infected with herpes virusVirology, 1958
- Cellular localization of herpes simplex virus by means of fluorescent antibodyVirology, 1956